Hypoxic-ischemic spinal cord injury following resuscitated cardiac arrest: a case series and rapid literature review Francoeur, C., Hornby, L., Lehr, A., Alkharusi, A., Gordon Boyd, J., Saint Martin, C., Poulin, C., Slater, F., Kirschen, M.P., Shemie, S.D. Can J Anesth / J Can Anesth (2025). https://doi.org/10.1007/s12630-025-02937-z
Organ donation after death determination by circulatory criteria: family members' experiences with withdrawal of life-sustaining measures in Canadian intensive care units Sarti, A., Sutherland, S., Meade, M., Weiss, M.J., Dhanani, S., Lotherington, K.M., Landriault, A., Vanderspank-Wright, B., Valiani, S., Keenan, S., Kramer, A.H., Beed, S., Brennan, J., Cardinal, P., Chassé, M., Nickerson, P., Shemie, S.D., Canadian Critical Care Trials Group (CCCTG). Can J Anaesth/J Can Anesth (2025). https://doi.org/10.1007/s12630-025-02978-4
Ethical issues in normothermic regional perfusion in controlled organ donation after determination of death by circulatory criteria: A scoping review Murphy, N.B., Slessarev, M., Basmaji, J., Blackstock, L., Blaszak, M., Brahmania, M., Chandler, J.A., Dhanani, S., Gaulton, M., Gross, J.A., Healey, A., Lingard, L., Ott, M., Shemie, S.D., Weijer, C. Transplantation (2025). https://doi.org/10.1097/tp.0000000000005161
Feasibility and optimization of Donation Advisor: a decision support tool for deceased organ donation and transplantationDhanani, S., Ramchandani, R., Allan, J., Hudek, N., Herry, C.L., Scales, N., Adhikari, N.K.J., Brehaut, J.C., Burns, K., Chassé, M., Iyengar, A., Meade, M.O., Ramsay, T., Scales, D.C., Selzner, M., Sener, A., Slessarev, M., Talbot, H., Weiss, M.J., Zaltzmann, J., Seely, A.J.E. Transplant Direct (2025). https://doi.org/10.1097/txd.0000000000001748
Canadian Highly Sensitized Patient Program report: A 1000 kidney transplants story Shamseddin, M.K., Paraskevas, S., Mainra, R., Maru, K., Piggott, B., Jagusic, D., Yetzer, K., Gunaratnam, L., Ribic, C., Kim, J., Singh, S., Hoar, S., Ramesh Prasad, G.V., Masse, M., Houde, I., Khalili, M., West, K., Liwski, R., Martin, S., Gogan, N., Karpinski, M., Monroy-Cuadros, M., Gourishankar, S., Johnston, O., Lan, J., Nguen, C., Gill, J., Pâquet, M. Can J Kidney Health Dis (2024). https://doi.org/10.1177/20543581241306811
Nova Scotia’s deemed consent for deceased organ donation: Family member perspectives and experiences in the ICU setting Sarti, A.J., Sutherland, S., Weiss, M.J., Landry, A., Hemming, H., Dirk, J., Lotherington, K., Beed, S. Transplant Direct (2024). https://doi.org/10.1097/txd.0000000000001713
Characteristics and practices of high-performing centers in organ donor identification and referral: A qualitative study Rotteau, L., Vaillancourt, S., Magaz, M., Lo, L., Wong, B.M., Lalani, J., Shemie, S.D., Zavalkoff, S. Can J Kidney Health Dis (2024). https://doi.org/10.1177/20543581241276362
Organ donation in Canadian PICUs: A cross-sectional survey, 2021-2022 Lee, L.A., Martin, D., Mahoney, M., James, L., Avitzur, Y., Carroll, A., Piggott, B., Tomlinson, C., Urschel, S., Hamiwka, L. Pediatr Crit Care Med (2024). https://doi.org/10.1097/pcc.0000000000003404
Organ donation following medical assistance in dying, Part I: a scoping review of legal and ethical aspectsSilva e Silva, V., Silva, A.M., Rochon, A., Lotherington, K., Hornby, L., Wind, T., Bollen, J., Wilson, L.C., Sarti, A.J., Dhanani, S. JBI Evid Synth (2024). https://doi.org/10.11124/jbies-22-00143
Advancing the scientific basis for determining death in controlled organ donation after circulatory determination of deathMurphy, N.B., Shemie, S.D., Capron, A., Truog, R.D., Nakagawa, T., Healey, A., Gofton, T., Bernat, J.L., Fenton, K., Khush, K., Schwartz, B., Wall, S. Transplantation (2024). https://doi.org/10.1097/tp.0000000000005002
Beliefs of physician directors on the management of devastating brain injuries at the Canadian emergency department and intensive care unit interface: a national site-level survey
Wtorek, P., Weiss, M.J., Singh, J.M., Hrymak, C., Chochinov, A., Grunau, B., Paunovic, B., Shemie, S.D., Lalani, J., Piggott, B., Stempien, J., Archambault, P., Seleseh, P., Fowler, R., Leeies, M. Beliefs of physician directors on the management of devastating brain injuries at the Canadian emergency department and intensive care unit interface: a national site-level survey. Can J Anesth/J Can Anesth (2024). https://doi.org/10.1007/s12630-024-02749-7
Navigating crossroads: exploring organ donation following medical assistance in dying Silva e Silva, Vanessa1; Silva, Amina Regina1; Lotherington, Ken2; Dhanani, Sonny3. Navigating crossroads: exploring organ donation following medical assistance in dying. JBI Evidence Synthesis 22(2):p 153-154, February 2024. | DOI: 10.11124/JBIES-23-00472
Donor audits in deceased organ donation: a scoping review | Vérifications des donneurs et donneuses dans le don d’organes après le décès : une étude de portée Amina Silva, PhD . Jehan Lalani, MHA . Lee James, MN . Shauna O’Donnell, MSc . Alexandre Amar-Zifkin, MLIS . Sam D. Shemie, MD . Samara Zavalkoff, MD Can J Anesth/J Can Anesth https://doi.org/10.1007/s12630-023-02613-0
Sociodemographic Variables in Canadian Organ Donation Organizations: A Health Information Survey Leeies, Murdoch MD, MSc; Ho, Julie MD; Wilson, Lindsay C. MHA; Lalani, Jehan MHA; James, Lee BSN, MN; Carta, Tricia RN, MN; Gruber, Jackie BA, MSc; Shemie, Sam D. MD; Hrymak, Carmen MD, MScHQ. Transplantation Direct 9(7):p e1494, July 2023. | DOI: 10.1097/TXD.0000000000001494
A Brain-based Definition of Death and Evidence based Criteria for its Determination after Arrest of Circulation or Neurologic Function in Canada: a 2023 clinical practice guideline Shemie, S.D., Wilson, L.C., Hornby, L. et al.
Editors’ Note: The evolution of critical care content in the Journal and a “special” Special Issue Schwarz, S.K.W., Jones, P.M. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02406-5
Answering global challenges to the determination of death: consensus-building leadership from Canada Gardiner, D., Greer, D.M., Bernat, J.L. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02423-4
An updated practice guideline for death determination: one giant leap for the field led by Canada Greer, D.M. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02405-6
What does "brainstem death" mean? A review of international protocols Spears WE, Lewis A, Bakkar A, Kreiger-Benson E, Kumpfbeck A, Liebman J, Sung G, Torrance S, Shemie SD, Greer DM. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02428-z. Epub ahead of print. PMID: 37131037
Brain-based arterial pulse pressure threshold for death determination: a systematic review Lalgudi Ganesan, S., Hornby, L., Weiss, M. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02425-2
Delayed recovery from severe refractory intracranial hypertension due to expansion of skin and pericranium stretch after decompressive craniectomy Cunan ET, Dudley RWR, Shemie SD. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02429-y. Epub ahead of print. PMID: 37131036
Ancillary investigations for death determination in infants and children: a systematic review and meta-analysis McKinnon NK, Maratta C, Zuckier LS, Boyd JG, Chassé M, Hornby L, Kramer A, Kromm J, Mooney OT, Muthusami P, Nitulescu R, Park J, Slessarev M, Basmaji J. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02418-1. Epub ahead of print. PMID: 37131035
Infratentorial brain injury and death by neurologic criteria in Canada: a narrative review Shemie, S.D., Briard, J.N., Boyd, J.G. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02427-0
Diagnostic test accuracy for cessation of circulation during death determination: a systematic review Klowak, J.A., Nguyen, AL.V., Malik, A. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02424-3
Ancillary radionuclide perfusion studies in the determination of death by neurologic criteria: methods, interpretation, and lexicon-a user guide for the clinician Zuckier LS, McKinnon NK. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02420-7. Epub ahead of print. PMID: 37131034
Diagnostic accuracy of ancillary tests for death by neurologic criteria: a systematic review and meta-analysis Neves Briard, J., Nitulescu, R., Lemoine, É. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02426-1
Radionuclide scintigraphy as an ancillary test for death determination in infants under 2 months of age McKinnon, N.K., Basmaji, J. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02419-0
The reticular activating system: a narrative review of discovery, evolving understanding, and relevance to current formulations of brain death Taran, S., Gros, P., Gofton, T. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02421-6
Autoresuscitation after circulatory arrest: an updated systematic review Zorko, D.J., Shemie, J., Hornby, L. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02411-8
Knowledge gaps in the definition and determination of death Maitre G, Shemie SD, Baker A, Chassé M, Hornby L, Sarti AJ, Teitelbaum J, Dhanani S. Can J Anaesth. 2023 May 2. doi: 10.1007/s12630-023-02422-5. Epub ahead of print. PMID: 37131033
Nontherapeutic research with imminently dying and recently deceased study populations: addressing practical and ethical challenges Murphy, N.B., Weijer, C., Lalgudi Ganesan, S. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02414-5
Legal considerations for the definition of death in the 2023 Canadian Brain-Based Definition of Death Clinical Practice Guideline Chandler, J.A., Pope, T.M. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02410-9
Consent for determination of death by neurologic criteria in Canada: an analysis of legal and ethical authorities, and consensus-based working group recommendations Pope TM, Chandler JA, Hartwick M. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02430-5. Epub ahead of print. PMID: 37131032
Trust and conflict in death determination—reflections on the legacy of Taquisha McKitty Stewart, S., McKitty, A., Chidwick, P. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02443-0
Balancing values: implications of a brain-based definition of death for pluralism in Canada Murphy, N.B., Chandler, J.A., Hartwick, M. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02408-3
Implications of the updated Canadian Death Determination Guidelines for organ donation interventions that restore circulation after determination of death by circulatory criteria Murphy, N.B., Weijer, C., Slessarev, M. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02413-6
Navigating disagreement and conflict in the context of a brain-based definition of death Simpson C, Lee-Ameduri K, Hartwick M, Shaul RZ, Kanji A, Healey A, Murphy NB, Pope TM. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02417-2. Epub ahead of print. PMID: 37131031
Potential pharmacological confounders in the setting of death determined by neurologic criteria: a narrative review Kanji S, Williamson D, Hartwick M. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02415-4. Epub ahead of print. PMID: 37131030
Death determination by neurologic criteria-what do families understand? Sarti AJ, Sutherland S, Meade M, Hornby L, Wilson LC, Landriault A, Vanderspank-Wright B, Valiani S, Keenan S, Weiss MJ, Werestiuk K, Beed S, Kramer AH, Kawchuk J, Cardinal P, Dhanani S, Lotherington K, Pagliarello G, Chassé M, Gatien M, Parsons K, Chandler JA, Nickerson P, Shemie S; Canadian Critical Care Trials Group (CCCTG). Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02416-3. Epub ahead of print. PMID: 37131029
Variability in criteria for death determination in the intensive care unit Shemie, J., Scales, N.B., Sucha, E. et al. Can J Anesth/J Can Anesth (2023). https://doi.org/10.1007/s12630-023-02412-7
When is a person dead? The Canadian public's understanding of death and death determination: a nationwide survey Sarti AJ, Honarmand K, Sutherland S, Hornby L, Wilson LC, Priestap F, Carignan R, Joanne B, Brewster H, Elliott-Pohl K, Weiss M, Shemie SD. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02409-2. Epub ahead of print. PMID: 37131025
Rationale for revisions to the definition of death and criteria for its determination in Canada Murphy NB, Hartwick M, Wilson LC, Simpson C, Shemie SD, Torrance S, Chandler JA. Can J Anaesth. 2023 May 2. English. doi: 10.1007/s12630-023-02407-4. Epub ahead of print. PMID: 37131021
Preventable harm in the Canadian organ donation and transplantation system: a descriptive study of missed organ donor identification and referral Zavalkoff S, O'Donnell S, Lalani J, Karam IF, James L, Shemie SD. Can J Anaesth. 2023 Mar 29. doi: 10.1007/s12630-023-02399-1. PMID: 36991298
Disparities in Deceased Donor Kidney Offer Acceptance: A Survey of Canadian Transplant Nephrologists, General Surgeons and Urologists. A. J. Vinson, H. Cardinal, C. Parsons, K. K. Tennankore, R. Mainra, K. Maru, D. Treleaven, J. Gill. 2023 Feb 23. doi: 10.1177/20543581231156855
In reply: Withholding therapeutic interventions in brain(stem) death: is it a self-fulfilling prophecy? Cunan ET, Dudley RWR, Shemie SD. Can J Anaesth. 2022 Sep 12. doi: 10.1007/s12630-022-02326-w. PMID: 36097131
Paediatric death after withdrawal of life-sustaining therapies: a scoping review protocol. Francoeur C, Hornby L, Silva A, Scales NB, Weiss M, Dhanani S. BMJ Open. 2022 Sep 19;12(9):e064918. doi: 10.1136/bmjopen-2022-064918.PMID: 36123110
The Experiences and Perceptions of Organ and Tissue Donation Coordinators Participating in a Team Cohesion and Communication Workshop: An Exploratory Descriptive Qualitative Study. Vanessa Silva e Silva, PhD, RN, Laura Hornby, MSc, Ken Lotherington, BSc., Andrea Rochon, MN, RN, Amina Regina Silva, MN, RN, Hilary Pearson, PhD, MA, Linda MacNutt, MSW, RSW Adrian Robertson, MD Kim Werestiuk, BN, RN, David Kuhl, PhD, MHSc, MD, Peggy John, Sonny Dhanani, BSc (Pharm), MD, FRCPC, and Aimee Sarti, MD. Published in CJCCN.
The experiences of family members of deceased organ donors and suggestions to improve the donation process: a qualitative study Aimee J. Sarti, Stephanie Sutherland, Maureen Meade, Sam Shemie, Angele Landriault, Brandi Vanderspank-Wright, Sabira Valiani, Sean Keenan, Matthew J. Weiss, Kim Werestiuk, Andreas H. Kramer, Joann Kawchuk, Stephen Beed, Sonny Dhanani, Giuseppe Pagliarello, Michaël Chassé, Ken Lotherington, Mary Gatien, Kim Parsons, Jennifer A. Chandler, Peter Nickerson and Pierre Cardinal; for the Canadian Critical Care Trials Group CMAJ August 08, 2022 194 (30) E1054-E1061; DOI: https://doi.org/10.1503/cmaj.220508
Flow is not perfusion, and perfusion is not function: ancillary testing for the diagnosis of brain death Guillaume Plourde MD, PhD, FRCPC, Joel Neves Briard MD, Sam D. Shemie MD, Jai Jai Shiva Shankar MD, DM, MSc, FRCPC & Michaël Chassé MD, PhD, FRCPC Canadian Journal of Anesthesia/Journal canadien d'anesthésie volume 68, pages953–961 (2021)
The impact of COVID-19 on the Canadian Kidney Paired Donation program: an opportunity for universal implementation of kidney shipping. McGregor TB, Sener A, Yetzer K, Gillrie C, Paraskevas S.Can J Surg. 2020 Sep-Oct;63(5):E451-E453. doi: 10.1503/cjs.012620.PMID: 33026312
Summaries of leading practices and guidelines along with accompanying peer reviewed publications can be found on initiative description pages here.
Archived reports
PDF copies of past reports have been archived and are available by request. A complete list of archived reports is available here.