Recent Updates

Modified on: 
Sep 9, 2021

Transfusion-related acute lung injury (TRALI) is a rare but serious syndrome characterized by sudden acute respiratory distress following transfusion. It is defined as new, acute respiratory distress during or within six hours of blood component (i.e., red blood cells, plasma, platelets) or blood product (i.e., plasma protein product) administration in the absence of temporally-associated risk factors for acute respiratory distress syndrome (ARDS). All plasma-containing blood components and plasma protein products have been implicated in TRALI, including rare reports with intravenous immunoglobulin (IVIg) and cryoprecipitate. Despite the very small amount of plasma contained in red blood cells, this component is associated with the largest number of reported cases of TRALI. TRALI is thought to be caused by activation of recipient neutrophils by donor-derived antibodies targeting human leukocyte antigens (HLA) or human neutrophil antigens (HNA). Non-antibody-mediated cases also occur and may be mediated by biologic response modifiers present in the transfused blood component or plasma protein product, along with recipient factors.

Transfusion
Published: 
Sep 7, 2021
Chapter 11

The approach to transfusion in emergent situations varies dramatically depending on the clinical scenario. The clinician’s assessment of the rapidity of bleeding, the severity of hemorrhage or amount of blood lost, and the clinical stability of the patient will determine the transfusion strategy.

Transfusion
Modified on: 
Aug 27, 2021

This annual report describes surveillance of transmissible blood-borne infections and emerging threats of concern. High quality and timely surveillance is central to the safety of the blood supply. This includes monitoring of transmissible disease markers that the blood is tested for and investigation of any reports of possible transfusion transmission, as well as a horizon scan for any new pathogens that may pose a risk. Non-infectious surveillance of aspects of donor health and safety as well as diagnostic services are also included.

Transfusion

Upcoming Events

When
September 23, 2021 | 12:00PM to 1:00PM
Where

Toronto/Webinar

Presented by:

Dr. Justyna Bartoszko
Physician and Assistant Professor at Toronto General Hospital,
Department of Anesthesia and Pain Management

Transfusion
When
September 28, 2021 | 12:00PM to 1:00PM
Where

Toronto/Webinar

Presented by:

Dr. Jacquie Trudeau

Objectives:

TBA

References:

TBA

 

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

Transfusion
When
October 5, 2021 | 12:00PM to 1:00PM
Where

Toronto/Webinar

Presented by:

Dr. Khalid Batarfi

Objectives:

TBA

References:

TBA

 

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

Transfusion

Blog

Modified on: 
Sep 16, 2021

Canadian Blood Services recently published its annual Surveillance Report, a summary of monitoring efforts related to transmissible infection testing in donors; possible transfusion-transmitted infections in recipients; and new, emerging pathogens. Surveillance also includes monitoring of donor safety.

Organs and Tissues
Stem Cells
Transfusion

Modified on: 
Sep 10, 2021

At the start of the pandemic, convalescent plasma was seen as potential therapy for treating COVID-19. But now, an international team led by Canadian scientists has published results from the largest clinical trial on convalescent plasma and COVID-19, showing it is not effective as a treatment against COVID-19.

Transfusion

Modified on: 
Sep 7, 2021

Transfusions can be a life-saving treatment for people living with sickle cell disease but finding compatible blood can be a challenge because Black and racialized donors—the ones with the best potential to match most SCD patients— are underrepresented in the donor pool. Read about initiatives that can support this patient group by improving the red blood cell inventory.

Transfusion