Recent Updates

Published: 
Sep 7, 2021
Chapter 11

The approach to transfusion in emergent situations varies dramatically depending on the clinical scenario. The clinician’s assessment of the rapidity of bleeding, the severity of hemorrhage or amount of blood lost, and the clinical stability of the patient will determine the transfusion strategy.

Transfusion
Modified on: 
Oct 6, 2021

Contributors: Utsav Patel, Canadian Blood Services manager of plasma protein products (PPP) formulary; Steven Drews, associate director of microbiology at Canadian Blood Services; Dimpy Modi, research analyst at Sunnybrook

Transfusion
Modified on: 
Sep 9, 2021

Transfusion-related acute lung injury (TRALI) is a rare but serious syndrome characterized by sudden acute respiratory distress following transfusion. It is defined as new, acute respiratory distress during or within six hours of blood component (i.e., red blood cells, plasma, platelets) or blood product (i.e., plasma protein product) administration in the absence of temporally-associated risk factors for acute respiratory distress syndrome (ARDS). All plasma-containing blood components and plasma protein products have been implicated in TRALI, including rare reports with intravenous immunoglobulin (IVIg) and cryoprecipitate. Despite the very small amount of plasma contained in red blood cells, this component is associated with the largest number of reported cases of TRALI. TRALI is thought to be caused by activation of recipient neutrophils by donor-derived antibodies targeting human leukocyte antigens (HLA) or human neutrophil antigens (HNA). Non-antibody-mediated cases also occur and may be mediated by biologic response modifiers present in the transfused blood component or plasma protein product, along with recipient factors.

Transfusion

Upcoming Events

When
October 28, 2021 | 12:00PM to 1:00PM
Where

Toronto/Webinar

Presented by:

TBA

Learning Objectives:

TBA

 

Note: This event is an Accredited Group Learning Activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.


 

Transfusion
When
November 2, 2021 | 12:00PM to 1:00PM
Where

Toronto/Webinar

Presented by:

Dr. Elina Vlachodimitropoulou

Objectives:

TBA

References:

TBA

 

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

Transfusion
When
November 9, 2021 | 12:00PM to 1:00PM
Where

Toronto/Webinar

Presented by:

Dr. Melanie Bodnar

Objectives:

TBA

References:

TBA

 

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

Transfusion

Blog

Modified on: 
Oct 5, 2021

The latest evidence on managing patients with massive hemorrhage, a major cause of potentially preventable deaths, is now available in a recently updated chapter of Canadian Blood Services’ Clinical Guide to Transfusion.

Transfusion

Modified on: 
Sep 29, 2021

A powerful collaboration between blood services, research institutions and industry leaders promises to advance blood transfusion therapy to new levels of precision and safety.

Transfusion

Modified on: 
Sep 28, 2021

The transfusion medicine traineeship support administered by Canadian Blood Services was recently renamed to honour Dr. Elianna Saidenberg — an expert in hematopathology and transfusion medicine and an inspirational physician and educator — who passed away in late 2019.

Transfusion