Molecular immunohematology refers to the detection of the molecular genetic basis of an antigen, rather than the antigen alone. Use of molecular testing in clinical laboratories requires knowledge of the molecular basis of blood group antigens and the availability of suitable genotyping methods that can be used in our testing environment.
By generously providing blood that can be manufactured into red blood cells, platelets and plasma products, whole blood donors are essential to the blood system and the patients it serves. Canadian Blood Services is committed to maintaining a safe and secure blood supply while also protecting the health of our blood donors. The focus of this article is the effect of red blood cell loss on the iron levels of the donor and the steps taken by Canadian Blood Services to protect the health of its donors.
In August 2017, Canadian Blood Services changed its platelet product testing procedure to improve the detection of bacterial contamination. This change enhanced the safety of Canadian Blood Services platelet products and provided the opportunity to improve inventory management by extending the platelet shelf life from five to seven days.
Transfusion-related acute lung injury (TRALI) is a rare but serious syndrome characterized by sudden acute respiratory distress following transfusion. It is defined as new, acute lung injury (ALI) during or within six hours after blood product administration in the absence of temporally-associated risk factors for ALI.