Topic teaching: Paediatric transfusion issues

Presented by

Dr. Sarah Tehseen
Assistant Professor Pediatric Hematology Oncology
Royal University Hospital, Saskatoon

Learning objectives

1. Recognize differences in neonatal hematology compared to adults
2. Outline differences in pre-transfusion testing in neonates
3. Review new evidence for transfusion of blood products in neonates
4. Identify the unique conundrums associated with transfusion
   1. Age of Blood
   2. Plasma transfusion-complications and appropriateness
   3. Alloimmunization
5. Understand large volume hemorrhage in neonates and its resuscitation
6. Unanswered questions and new avenues

References

1. Sokou R et al. Fresh frozen plasma transfusion in the neonatal population: A systematic review. Blood Rev. 2022 Sep;55:100951. 
2. Murphy CA et al. The role of the calibrated automated thrombogram in neonates: describing mechanisms of neonatal haemostasis and evaluating haemostatic drugs. Eur J Pediatr. 2022 Jan;181(1):23-33. 
3. Juul SE et al. Effect of High-Dose Erythropoietin on Blood Transfusions in Extremely Low Gestational Age Neonates: Post Hoc Analysis of a Randomized Clinical Trial. JAMA Pediatr. 2020 Oct 1;174(10):933-943.
4. Juul SE et al. A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants.  N Engl J Med. 2020 Jan 16;382(3):233-243. 
5. Kirpalani H et al. Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants.  N Engl J Med. 2020 Dec 31;383(27):2639-2651.
6. Lau W. Clinical Guide to Transfusion, Chapter 13, Neonatal and Paediatric Transfusion.  

Note: The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

Registration  

Closed

Appraisal

Please click here for the Appraisal Link

The survey will close November 4th at 5 p.m. Eastern.

To be added to the distribution list for the LearnTransfusion series, send an email to learn.transfusion@blood.ca  with “Weekly Transfusion Medicine Seminars” in the subject line. Include your name and complete e-mail address in the body of the e-mail and confirm that you would like to be added to the distribution list for the LearnTransfusion series. You will then receive weekly email notifications of upcoming series events with details on how to join the webinars (e.g.,  link to register for the webinar).

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services, is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.