Topic Teaching: Neonatal Transfusion Tidbits

Speaker:

Dr. Lani Lieberman, MD, FRCPC
Assistant Professor, Laboratory Medicine and Pathology
University of Toronto
Co-Medical Director, Blood and Transfusion Services
Universith Health Network Hospital

Objectives:

1.  Discuss the pathophysiology of neonatal jaundice and management strategies when jaundice is severe.
2.  Review transfusion related neonatal adverse events, particularly necrotizing enterocolitis.
3.  Review recent trials focusing on neonatal platelet transfusions.

References:

1.  Zwiers C et al. Immunoglobulin for alloimmune hemolytic disease in neonates.  Cochrane Database of Systematic Reviews 2018, Issue 3. Art. No.: CD003313.  DOI: 10.1002/14651858.CD003313.pub2.
2.  Murki et al.  Blood exchange transfusion for infants with severe neonatal hyperbilirubinemia. 2011; Semin Perinatology;35; 175-184.
3.  Garg et al.  Transfusion-associated necrotizing enterocolitis in preterm infants: An updated meta-analysis of observational data.  Journal of Perinatal Medicine 2018; 46(6): 677-685.
4.  Rai et al Transfusion-associated necrotizing enterocolitis re-evaluated: A systemic review and meta-analysis.  Journal of Perinatal Medicine 2018; 46(6): 665-676.
5.  Curley et al.  Randomized Trial of Platelet Transfusion Threshold in Neonates.  NEJM 2018: 380(3): 242-251, 2019.

Note:  The session is a self-approved group learning activity (Section 1) as defined by the Maintenance of Certification program of The Royal College of Physicians and Surgeons of Canada.

To register for the LearnTransfusion series, send an email to learn.transfusion@blood.ca with  “Weekly Transfusion Medicine Seminars” in the subject line. Include your name and complete e-mail address in the body of the e-mail, and confirm that you would like to register for the LearnTransfusion series. You will then receive weekly email notifications of upcoming series events with details on how to join the webinars (e.g., call-in number and a link to register for the webinar).

The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine.