AABB ecasts

Simple Transfusion vs. Exchange Transfusion and Future Therapies in Patients with Sickle Cell Disease

September 15, 2021 | 2:00PM to 3:30PM (EDT)


Program Description

Sickle cell disease is affected approximately 100,000 people in the United States. It is a major public health concern and the patients have a significant morbidity and mortality. At this time, transfusion of red blood cells (RBCs) is one of the main treatment strategies for this disease. However, transfusion is potentially associated with multiple complications, including transfusion-transmitted infections and alloimmunizations. 

Given that there are few quality studies investigated the effect of simple vs. exchange transfusion in patients with sickle cell disease, this program will summarize the current data and expert opinion on the use of each treatment modality. Key considerations that physicians should be aware of when choosing between treatment options as well as challenges in pediatric patients will also be addressed. Lastly, novel therapies in the treatment of sickle cell disease, including cellular therapies, will be discussed.

Learning Objectives

After participating in this educational activity, participants should be able to:

  • Discuss considerations for simple vs. exchange transfusions in patients with sickle cell disease.
  • Summarize key considerations in using different treatment options in pediatric patients.
  • Describe current novel therapies, including cellular therapies, as treatment modalities in sickle cell disease.


Registration includes access to both the live and on-demand version of this eCast.

AABB understands the value of learning together as a group but with COVID-19, bringing everyone together to share the experience in person may not be an option for your team. Given this, all participants in a group will be provided the ability to register as a single viewer (AABB will provide a promocode to registered group viewing coordinators to share with their team in advance of the live program). If you are a facility interested in participating in this eCast, simply complete the Group Viewing registration form and AABB will provide detailed instructions to share with your team. For single viewers, the process has not changed – simply click on the Register button below to register.

Please note: registration for the live eCast will close 1 hour prior to the eCast start time. If you register after this time you will receive access to the on-demand eCast when it is available.


Click here for additional information and to register.