The Centre for Blood Research

Seminar Series: Innovative strategies for replacing IVIg in autoimmune disease - the role of Fc receptor blockade


Event details

This lecture is part of the CBR seminar series.

IVIg, a long-established treatment for autoimmune and inflammatory conditions involving IgG and FcγRs, faces serious supply constraints. Our research delves into IVIg's mechanisms, highlighting the potential of FcγR blockade as a lab-made IVIg substitute, as demonstrated in FcγR-humanized mice. This recent work offers promising avenues for enhancing treatment accessibility and efficacy.

Presented by

Dr. Alan Lazarus
Professor, Departments of Medicine and Laboratory Medicine, University of Toronto
Senior Scientist, Canadian Blood Services
Scientist, St. Michael's Hospital (Unity Health)


For information about CBR Seminar series events, visit the CBR website: CBR Seminars | Centre for Blood Research ( To receive Zoom access details for CBR Seminar series events, contact Kaitlyn Chuong (