The FARES-II trial: Is it time to replace FP with PCC as first-line therapy for coagulopathic bleeding in cardiac surgery?

Join the next Breakthroughs in blood: Advancements into action webinar as Dr. Keyvan Karkouti discusses Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery: The FARES-II Multicenter Randomized Clinical Trial published in JAMA in March 2025. The webinar will take place Monday June 16th, 1pm-2pm (ET).  

We invite you to take part in a round table panel discussion during the 1-hour webinar to understand more about the impact of this study on your current practice.

Presented by

Keyvan Karkouti, MD, FRCPC, MSc
Anesthesia, University of Toronto

Moderated by

Jeannie Callum, MD, FRCPC
Transfusion Medicine, Kingston Health Sciences Centre

Panelists

Asim Alam, MD, FRCPC, DRCPSC
Transfusion Medicine, Canadian Blood Services

Joel Price, MD, MPH, FRCSC
Cardiac Surgery, Vancouver General Hospital/Vancouver Coastal Cardiac Surgery

Mullein Thorleifson, MD, FRCPC
Cardiac Anesthesia, University of Manitoba

Learning Objectives

1. Learn about the pathophysiology of hemostatic impairments after cardiac surgery
2. Review the trials conducted before FARES-II comparing PCC to plasma
3. Review the results of the FARES-II trial on patient efficacy and safety outcomes
4. Discuss the impact of the transition from plasma to PCC for cardiac surgery programs and the transfusion services

Prior to attending this webinar, it is recommended to read the trial publication: Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery: The FARES-II Multicenter Randomized Clinical Trial

Registration

Register for the Zoom meeting here.

Downloadable event poster available below:

Breakthroughs in blood: Advancements into action

The Breakthroughs in blood: Advancements into action webinar series is curated for health-care professionals, hospital administrators, policy-makers, and researchers who want to stay up to date on advances in blood research and best practices. Hosted by the esteemed Dr. Jeannie Callum and coordinated by Canadian Blood Services, this series delves into the "So what?" and "Now what?" of blood science and medical research, with a dedicated focus on transfusion clinical trials and guidelines.

Don't miss this unique opportunity to advance your knowledge and take actionable steps toward a better healthcare future.

Resources

The Breakthroughs in blood: Advancements into action recording, dissemination, and implementation resources are made available at Breakthroughs in blood: Advancing practice through research | Professional Education.