Seminar series: Regulatory T cell functional plasticity in colorectal cancer progression

This lecture is part of the CBR lecture series. Held on Wednesdays from 1-2pm PT, CBR seminars feature insightful scientific talks, with speakers from a range of clinical, industry and academic backgrounds.

My lab studies regulation of inflammation in CRC with focus on the role of peripherally induced Tregs. I will provide an overview of our studies on the gain of tumor promoting properties by RORgt+ Tregs and the underlying molecular mechanisms, mostly dealing with the epigenetic changes introduced by the beta-catenin/TCF-1 signaling pathway and gut dysbiosis.

Presented by

Dr. Khash Khazaie
Professor/Consultant, Department of Immunology, Mayo Clinic

Registration

For information about CBR Seminar series events, visit the CBR website: CBR Seminars | Centre for Blood Research (ubc.ca). To receive Zoom access details for CBR Seminar series events, contact Kaitlyn Chuong (kaitlyn.chuong@ubc.ca).