Seminar Series: Structure guided therapeutic discovery targeting virulence and antibiotic resistance mechanisms in blood borne pathogens

Event details

This lecture is part of the CBR lecture series. Held on Wednesdays from 1-2pm PT, CBR seminars feature insightful scientific talks, with speakers from a range of clinical, industry and academic backgrounds.

Structural biology and drug discovery often go hand in hand, with the atomic details from xray crystallography and single particle cryo electron microscopy (cryo-EM) providing molecular blueprints for understanding target mechanism of action and optimization of lead molecules that block function to fight disease. The Strynadka laboratory use sophisticated engineered expression systems to produce and characterize membrane localized targets in pathogenic bacteria of clinical import including the nosocomial Staphlococcus aureus and Pseudomonas aeruginosa. Four examples will be illustrated with essential roles in virulence and/or drug resistance in these notoriously antibiotic resistant strains and infections.

Presented by

From the lab of: Dr. Natalie Strynadka, Department of Biochemistry, UBC

Presented by: Alek Lazarski, Wes Mosimann & Helena Sverak

Registration

For information about CBR Seminar series events, visit the CBR website: CBR Seminars | Centre for Blood Research (ubc.ca). To receive Zoom access details for CBR Seminar series events, contact Kaitlyn Chuong (kaitlyn.chuong@ubc.ca).