Seminar series: Keeping up with the TEMPO in the omics era

This lecture is part of the CBR lecture series. This lecture is part of the CBR lecture series. Held on Wednesdays from 1-2pm PT, CBR seminars feature insightful scientific talks, with speakers from a range of clinical, industry and academic backgrounds.

What time is it? Can different cells give different answers to the question “what time is it?”

Do humans have internal clocks that can “tell” gene transcript to turn on and become proteins? How do these clocks work during aging and are these clocks inaccurate during diseases?

Are these clocks the same within different cell types?

Our team created a “proteomic clock” atlas of the eye using 120 human patients. From this data, we can begin to better predict a healthy person’s age based on their protein profile. The clock revealed that diseases such as diabetic retinopathy, Parkinson’s disease and uveitis cause accelerated aging within specific cell types.

Presented by

Dr. Tony Dufour
Associate Professor, University of Calgary
Associate Professor, McCaig Institute
Scientific Director, Southern Alberta Mass Spectrometry (SAMS) Core Facility

Registration

For information about CBR Seminar series events, visit the CBR website: CBR Seminars | Centre for Blood Research (ubc.ca). To receive Zoom access details for CBR Seminar series events, contact Kaitlyn Chuong (kaitlyn.chuong@ubc.ca).