Autoimmune HIT: implications for understanding autoimmunity

Dr. Andreas Greinacher
Head of the Institute of Immunology and Transfusion Medicine, University Hospital Greifswald, Germany

• Define "autoimmune HIT (aHIT)"
• Role of biophysical methods for single antibody studies
• Implications for new mechanisms of autoimmunity

1. Greinacher A, Selleng K, Warkentin TE. Autoimmune heparin-induced thrombocytopenia. J Thromb Haemost 2017 Nov; 15 (11): 2099-2114.
2. Nguyen TH, Medvedev N, Delcea M, Greinacher A. Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity. 2017 May 22;8:14945.

The session is a self-approved group learning activity (Section1) as defined by the Maintenance of Certification program of the Royal College of Physicians and Surgeons of Canada. The LearnTransfusion series is the seminar component of the Areas of Focused Competency (AFC)-Diploma Program in Transfusion Medicine. The series, organized by Canadian Blood Services is also open to all practitioners in the field of Transfusion Medicine. Through a series of regular webinars, trainees and practitioners are exposed to various scientific, technical and clinical aspects of transfusion medicine. For more information about the LearnTransfusion series and how to register visit LearnTransfusion series.